isonic medical, glaucoma testing, vibration tonometry

a quantum leap in glaucoma detection and monitoring


iSonic Medical receives the Medical Innovation Cluster Label

for their innovative work in Glaucoma detection and monitoring.

Vibration Tonometry

A clinical stage ophthalmological device company building precise, non-contact tonometers based on a novel vibration technology for measuring intraocular  pressure or eye pressure (IOP)


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Glaucoma, 2nd leading cause

of blindness worldwide


•  Affects 2-3%  over the age of 40 years

•  2x more  over 65 ans

•  50% unaware they are affected

•  80 million affected worldwide by 2020

•  Leads to blindness in 10% of subjects

•  Blindness, a growing problem in public healthcare…

•  Direct costs:   US$ 2 300 billion

•  Indirect costs: US$   652 billion

         …Yet, according to the WHO, avoidable in 80% of cases



Urgent needs

•  Necessity to measure Eye pressure (IOP) simply and in all places

   of care to diagnose the illness early

•  Necessity of frequent measures in the home by self-

   measurement as is done with blood pressure





Detection, diagnostic and monitoring of glaucoma – Current practice



Principal approach to treatment

Current practice

Today : Two types of tonometers

Ineffective in certain cases :

Contact tonometers are often not easy to use:


Accurate, contact tonometers

(Goldmann): The « gold standard » but invasive, require local anesthesia, operator dependent





•  >21 mm Hg (level at which glaucoma is diagnosed)

•  Thin corneas (measurement errors)

• “Post-refractive surgery” corneas  (actually impossible today )


•  Specialist only device – measurement can only be taken

   during doctor’s office hours

•  Patient must be seated and not lying down

Non-invasive models

(airpuff): notoriously inaccurate





iSonic’s solution : Vibration Tonometry

•  Flattening of cornea with isonic tonometer: 0.1 µm

    (flattening with Goldmann tonometer: 100 µm)

•   Average thickness of cornea: 540 µm


No change in volume or pressure of eye with i Sonic tonometer



Excitation causes slight vibration of eye


IOP inferred from vibrational response of  cornea



Clinical Stage of Development

A patented technology


iSonic’s Ambition

Radically improve glaucoma screening, diagnosis & monitoring





Measurement capabilities





Easy and rapid measurements



Avoidance of all infectious, traumatic and allergic risks (related to local anaesthetics)


High IOP (>21 mm Hg)

Thin and surgically treated corneas

Repetitive measures improve precision

Corneal Elasticity Measurement


Operator independent



Professional tonometers

Homecare tonometer

Better monitoring and understanding of glaucoma… to delay vision loss and reduce healthcare costs




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